API Acidum obeticholicum CAS 459789-99-2 ad imaginem biliari cholangitis Featured

API Acidum obeticholicum CAS 459789-99-2 pro biliario cholangitis

Description:

Acidum obeticholicum solum vel in compositione curationis cuiusdam morbi hepatis (cholangitis-PBC biliarii primi).

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Product Detail

Product Tags

Descriptio

Acidum obeticholicum solum vel in compositione curationis cuiusdam morbi hepatis (cholangitis-PBC biliarii primi).

Specificatio:

Product Name	Obeticholic Acidum
Nomen chemicum	6-Acidi Ethylchenodeoxycholic
Alia Nomen	3A, 7A -DIHYDROXY-6A -ETHYL-5B-CHOLAN-XXIV-OIC ACIDUM; Acidum obeticholicum 6-ECDCA; acidum 6alpha-ethyl-chenodeoxycholicum;6-Ecdca;6-Ethylchenodeoxycholicum;6alph;acidum obeticholicum (INT 747,6 -ECDCA)
CAS Number	459789-99-2
Formulae hypotheticae	C26H44O4
Formula Pondus	420.63
Aspectus	Pulvis albus
Assay	99.0% min
Density	1.091 g/cm3
Liquescens punctum	108-110 °C
Ferveret	562.9±25.0 °C
sarcina	20kg/peram/orum, 25kg/peram/orum, vel quod requiris
Repono	Repone continens arcte clausus in loco sicco & frigido.Non exponere solis dirigere.
COA & MSDS	Praesto

Consuetudinem

Acidum obeticholicum est acidum dihydroxybeta-cholanicum quod est acidum chenodeoxycholicum portans adiecto ethyl substituente in 6alpha-positione.Acidum semi-syntheticum bilis, quae in receptore farnesoideo X agit, et ad cholangitis biliaris primarii curationem adhibetur.Partes habet sicut receptor agonist farnesoidis X et agens hepatoprotectivum.Est acidum dihydroxum-5beta-cholanicum, steroidum 3alpha-hydroxum et steroidum 7alpha-hydroxy.Acidum chenodeoxycholicum trahit.
Acidum obeticholicum (OCA) est synthetice bilis acidum modificatum et potens agonista receptoris farnesoidis X nuclei (FXR) quod adhibetur ad curandum morbos hepatis cum primis cholangitis biliariis.